According to research findings, NMN acts quickly! Preclinical studies on the pharmacokinetics of NMN suggest that it is absorbed from the gut into the bloodstream within minutes and transported into tissues within 10 to 30 minutes [1, 2]. Then the magic (or biochemistry) begins! NMN is immediately used for NAD⁺ biosynthesis. Research indicates that this rapid absorption is enabled by an NMN-specific transporter called “SLC12A8”.

Same day, more cellular activity. Human studies show that NAD⁺ metabolites in blood plasma begin to rise within the first few hours after taking NMN – and continue to rise steadily, indicating increased NAD⁺ utilization in cells and tissues [4]. Your cells are already using the boosted NAD⁺ levels to support hundreds of essential cellular processes. If you could talk to your cells, they’d definitely thank you!

NAD⁺ levels continue to rise and now benefit the powerhouses of your cells – the mitochondria, where cellular energy is produced. A preclinical study showed that a three-day treatment of human kidney cells with NMN led to increased mitochondrial replication [5]. An increased number of mitochondria allows for more efficient energy production and metabolic regulation within the cell.

Fact: After one month, NAD⁺ levels in the blood are up to 40% higher compared to when you took your first capsules. They will remain at this elevated level as long as you continue supplementing. This is based on a human clinical study in which a daily dose of 250 mg NMN was administered to healthy adults [7]. Can you already feel the boost in energy and fitness?

We’re moving from cells to entire systems, as aspects of your physical fitness may begin to improve. A human clinical study showed that NAD⁺ is one of the most depleted metabolites in aging muscle, and that higher NAD⁺ levels were associated with better muscle function [8]. Another clinical trial found that taking 250 mg of NMN daily for 6 weeks improved muscle strength and performance in healthy older men [19].

How does your skin look? Advanced glycation end-products (AGEs) are markers of skin aging. A clinical study in healthy postmenopausal women found that eight weeks of NMN supplementation (300 mg per day) led to a reduction in AGEs in the skin – a change considered a positive effect on skin aging [10].

It’s been three months, and your cells and tissues have enjoyed 40% more NAD⁺ for a full 60 days. But what has changed physically? A lot, as clinical studies show... One study found that healthy older men taking 250 mg of NMN daily experienced an improvement in gait speed (walking speed) [9]. Another study found that a daily dose of 300 mg NMN led to a doubling of telomere length in peripheral blood mononuclear cells – indicating a younger biological age! [12]

A lot can happen in six months – what has changed in your life? With beLIVELY NMN, everything begins to add up to system-wide health benefits. It provides sustainable support for multiple tissues and systems by targeting metabolic aging at its root – inside your cells. Have you ever thought about testing your biological age? After six months of NMN supplementation, it may be significantly lower than before –because your cells have finally found the energy driver they’ve been waiting for: NMN.